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Before starting prozac, tell your healthcare provider if you: Are taking certain drugs or treatments such as: Triptans used to treat migraine headache Medicines used to treat mood, anxiety, psychotic or thought disorders, including tricyclics, lithium, buspirone, ssris, snris, maois orantipsychotics Amphetamines. Concomitant use of other highly protein-bound drugs can increase the concentration of prozac see contraindications, warnings AND precautions, Potential For prozac To affect Other Drugs, and clinical pharmacology. For more information about prozac call 1-800-Lilly-Rx ( ). Families and caregivers of patients should be advised to look for the emergence of such symptoms on a day-to-day basis, since changes may be abrupt. Reported clinical findings have included respiratory distress, cyanosis, apnea, seizures, temperature instability, feeding difficulty, vomiting, hypoglycemia, hypotonia, hypertonia, hyperreflexia, tremor, jitteriness, irritability, and constant crying. However, there is substantial evidence from placebo-controlled maintenance trials in adults with depression that the use of antidepressants can delay the recurrence of depression.

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Report any new or worsening symptoms to your doctor. Around 1 in 10 people in the United States (U.S.) are thought to use ssri drugs, and 1 in 4 women in their 40s and 50s. Coadministration of fluoxetine with other drugs that are metabolized by CYP2D6, including certain antidepressants (e.g., TCAs antipsychotics (e.g., phenothiazines and most atypicals and antiarrhythmics (e.g., propafenone, flecainide, and others) should be approached with caution. Antagonism of muscarinic, histaminergic, and 1-adrenergic receptors has been hypothesized to be associated with various anticholinergic, sedative, and cardiovascular effects of classical tricyclic antidepressant (TCA) drugs. Musculoskeletal System - Infrequent : arthritis, bone pain, bursitis, leg cramps, tenosynovitis; Rare : arthrosis, chondrodystrophy, myasthenia, myopathy, myositis, osteomyelitis, osteoporosis, rheumatoid arthritis. Some medications (such as metronidazole, disulfiram ) can cause a serious reaction when combined with alcohol. Give a list of all your medicines to any healthcare provider who treats you. Table 1 demonstrates the appropriate individual component doses of prozac and olanzapine versus Symbyax. A specific effect on bone development was reported in juvenile mice administered fluoxetine by the intraperitoneal route to 4 week old mice for 4 weeks at doses.5 and 2 times the oral mrhd of 20 mg/day on mg/m2 basis. Open-angle glaucoma is not a risk factor for angle-closure glaucoma.

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Prozac is a prescription medicine used to treat depression. Patients should be advised of the signs and symptoms associated with serotonin syndrome that may include mental status changes (e.g., agitation, hallucinations, delirium, and coma autonomic instability (e.g., tachycardia, labile blood pressure, dizziness, diaphoresis, flushing, hyperthermia neuromuscular changes (e.g., tremor, rigidity, myoclonus, hyperreflexia. Patients should be advised of the following issues and asked to alert their prescriber if these occur while taking prozac as monotherapy or in combination with olanzapine. Among 633 adult patients who overdosed on fluoxetine hydrochloride alone, 34 resulted in a fatal outcome, 378 completely recovered, and 15 patients experienced sequelae after overdosage, including abnormal accommodation, abnormal gait, confusion, unresponsiveness, nervousness, pulmonary dysfunction, vertigo, tremor, elevated blood pressure. Weight loss was reported.4 of patients treated with prozac and.5 of patients treated with placebo. These studies did not show an increase in the risk of suicidal thoughts and behavior with antidepressant use in patients over age 24; there was a reduction in risk with antidepressant use in patients aged 65 and older see warnings AND. It is also marketed for the treatment of premenstrual dysphoric disorder sarafem, fluoxetine hydrochloride). Withdrawal Patients who suddenly reduce their dose or stop taking Prozac may experience a number of unwanted effects. Call your doctor for medical advice about side effects. The risk of QT prolongation may be increased if you have certain medical conditions or are taking other drugs that may cause QT prolongation. In an intermittent-dosing placebo controlled trial, no reactions associated with discontinuation reached an incidence of 2 for sarafem.

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