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This component is active against microorganisms developing in an oxygen-free environment. The MIC values should be interpreted according to the criteria provided in the following Table Susceptibility Test Interpretive Criteria for Metronidazole against Anaerobes* MIC (mcg/mL) Interpretation 8 Susceptible (S) 16 Intermediate (I) 32 Resistant (R) *Agar dilution method is recommended. Methods for Antimicrobial Susceptibility Testing of Anaerobic Bacteria; Approved Standard - Eighth Edition. In this case, the patient requires medical symptomatic treatment. Endocarditis caused by Bacteroides species including the. In case of drug overdose, seek medical attention immediately.
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No dosage adjustment is needed for patients with mild to moderate hepatic impairment. Flagyl and, flagyl,. Microbiology Mechanism Of Action Metronidazole, a nitroimidazole, exerts antibacterial effects in an anaerobic environment against most obligate anaerobes. Stop taking the medicine and call your doctor right away if you have neurologic side effects (more likely to occur while taking metronidazole long term numbness.
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The use of this medication may lead to disturbances of the digestive system stomach pains, nausea, loss of appetite and so forth. Central nervous system (CNS) infections, including meningitis and brain abscess, caused by Bacteroides species including the. There are published data from case-control studies, cohort studies, and 2 meta-analyses that include more than 5000 pregnant women who used metronidazole during pregnancy. HOW supplied flagyl 250-mg tablets are round, blue, film coated, with searle and 1831 debossed on one side and flagyl and 250 on the other side; supplied as bottles of 50 and 100. In pregnant patients for whom alternative treatment has been inadequate, the one-day course of therapy should not be used, as it results in higher serum levels which can reach the fetal circulation (see precautions, Pregnancy ). Inactive ingredients include cellulose, FD C Blue. Vaginalis infection in females and males when the presence of the trichomonad has been confirmed by appropriate laboratory procedures (wet smears and/or cultures). Please consult your doctor for exact dosing instructions. See detailed T C here. Less than 20 of the circulating metronidazole is bound to plasma proteins.